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Development of a dual temperature control system for isoprene biosynthesis in

《化学科学与工程前沿(英文)》 2022年 第16卷 第7期   页码 1079-1089 doi: 10.1007/s11705-021-2088-0

摘要: Conflict between cell growth and product accumulation is frequently encountered in the biosynthesis of secondary metabolites. To address the growth-production conflict in yeast strains harboring the isoprene synthetic pathway in the mitochondria, the dynamic control of isoprene biosynthesis was explored. A dual temperature regulation system was developed through engineering and expression regulation of the transcriptional activator Gal4p. A cold-sensitive mutant, Gal4ep19, was created by directed evolution of Gal4p based on an internally developed growth-based high-throughput screening method and expressed under the heat-shock promoter PSSA4 to control the expression of PGAL-driven pathway genes in the mitochondria. Compared to the control strain with constitutively expressed wild-type Gal4p, the dual temperature regulation strategy led to 34.5% and 72% improvements in cell growth and isoprene production, respectively. This study reports the creation of the first cold-sensitive variants of Gal4p by directed evolution and provides a dual temperature control system for yeast engineering that may also be conducive to the biosynthesis of other high-value natural products.

关键词: transcriptional activator     directed evolution     dynamic control     heat-shock     isoprene    

Constant temperature control of tundish induction heating power supply for metallurgical manufacturing

Yufei YUE, Qianming XU, Peng GUO, An LUO

《能源前沿(英文)》 2019年 第13卷 第1期   页码 16-26 doi: 10.1007/s11708-018-0572-0

摘要: The tundish induction heating power supply (TIHPS) is one of the most important equipment in the continuous casting process for metallurgical manufacturing. Specially, the constant temperature control is greatly significant for metallurgical manufacturing. In terms of the relationship between TIH load temperature and output power of TIHPS, the constant temperature control can be realized by power control. In this paper, a TIHPS structure with three-phase PWM rectifiers and full-bridge cascaded inverter is proposed. Besides, an input harmonic current blocking strategy and a load voltage feedforward control are also proposed to realize constant temperature control. To meet the requirement of the system, controller parameters are designed properly. Experiments are conducted to validate the feasibility and effectiveness of the proposed TIHPS topology and the control methods.

关键词: tundish induction heating power supply (TIHPS)     constant temperature control     input harmonic current blocking     load voltage feedforward    

Temperature effects of shape memory alloys (SMAs) in damage control design of steel portal frames

Xiaoqun LUO, Hanbin GE, Tsutomu USAMI

《结构与土木工程前沿(英文)》 2012年 第6卷 第4期   页码 348-357 doi: 10.1007/s11709-012-0176-4

摘要: The objective of the present study is to analytically investigate temperature effects of an axial-type seismic damper made of shape memory alloys (SMAs) equipped in steel frames. Based on a modified multilinear one dimensional constitutive model of SMAs, two types of SMAs are employed, which have different stress plateau and different stress growth rate with temperature increase. Temperature effects of SMA dampers on seismic performance upgrading are discussed in three aspects: different environment temperatures; rapid loading rate induced heat generation and different SMA fractions. The analysis indicates that the effect of environment temperature should be considered for the SMA damper in steel frames. However, the rapid loading rate induced heat generation has little adverse effect.

关键词: damage control design     shape memory alloy     temperature effect    

Temperature control of transfer roller’s bearing based on finite element analysis

Peng ZHANG, Yourong LI, Han XIAO

《机械工程前沿(英文)》 2009年 第4卷 第2期   页码 215-218 doi: 10.1007/s11465-009-0026-9

摘要: After a heat preservation cover is installed on the main rolling line, the heat dissipation environment of the transfer roller working on the heat preservation cover is changed. To ensure the normal production, a reasonable working jet capacity of the roller neck is derived. First, a globe model of the transfer roller is built for finite element analysis. Second, the sub-model of the fixed end bearing is built and the boundary condition of the sub-model is supplied by the results of the globe model. The analysis result of the sub-model shows that the temperature of the transfer roller bearing exceeds 85°C a rolling periodicity later. With finite element analysis, the heat flux is obtained and the minimum working jet capacity is derived.

关键词: transfer roller bearing     finite element analysis     sub-model     temperature control    

空调客车内温度控制系统仿真研究

于梅春,张登春

《中国工程科学》 2006年 第8卷 第7期   页码 83-88

摘要:

分别采用模糊控制方法与常规PID控制方法,对空调客车内温度控制系统进行了仿真研究。仿真结果表明,PID控制能消除稳态误差,但超调大,过渡时间长,在工况变化较小的情况下,能满足一定的控温要求;对于对象延迟、工况变化较大的场合,模糊控制能实时跟踪空调工况变化,较快地达到控温目标值,节能率高,综合控制效果比PID要好。

关键词: 空调客车     温度控制     模糊控制     仿真    

Sliding window games for cooperative building temperature control using a distributed learning method

Zhaohui ZHANG, Ruilong DENG, Tao YUAN, S. Joe QIN

《工程管理前沿(英文)》 2017年 第4卷 第3期   页码 304-314 doi: 10.15302/J-FEM-2017045

摘要: In practice, an energy consumer often consists of a set of residential or commercial buildings, with individual units that are expected to cooperate to achieve overall optimization under modern electricity operations, such as time-of-use price. Global utility is decomposed to the payoff of each player, and each game is played over a prediction horizon through the design of a series of sliding window games by treating each building as a player. During the games, a distributed learning algorithm based on game theory is proposed such that each building learns to play a part of the global optimum through state transition. The proposed scheme is applied to a case study of three buildings to demonstrate its effectiveness.

关键词: game theory     demand response     HVAC control     multi-building system    

载人航天器微量污染净化装置温度控制研究

庞丽萍,王浚

《中国工程科学》 2007年 第9卷 第4期   页码 60-63

摘要:

催化氧化器是载人航天器中的微量污染净化装置的一个重要组成部分。提出了一种新型自整定模糊 控制器控制催化氧化器工作温度,它采用在线Bang-bang方法获得系统特性,利用所提出的整定公式计算出模糊 控制器的输入输出因子,将这些比例因子与标准查寻表结合,实现了自整定模糊控制器的设计。

关键词: 载人航天器     催化氧化器     温度控制     模糊控制     自整定    

卫星主动控温回路的设计模型与算法

李运泽,杨娟,宁献文,王晓明,石晓波

《中国工程科学》 2008年 第10卷 第7期   页码 48-50

摘要:

使用电加热器的卫星主动控温回路是一种重要的主动热控措施,通过简明扼要的机理分析建立起该主动控温过程中受控对象温度变化的动态方程,得出了稳态控温、瞬态控温两种基本的控温模式下主动控温回路电加热器功率需求的计算表达式,给出了进行主动控温回路电加热器热功率设计计算的一般流程,较详细地分析了一个具体设计算例,为卫星主动控温回路设计计算提供了简便的计算模型和方法。

关键词: 卫星     主动热控制     主动控温回路     模型与算法    

A novel high-temperature and high-pressure hydraulic pump based on mononeuron control

Linhui ZHAO, Xin FANG

《机械工程前沿(英文)》 2009年 第4卷 第2期   页码 219-223 doi: 10.1007/s11465-009-0024-y

摘要: Based on structures and characteristics of traditional hydraulic pumps, this paper proposes a novel high-temperature and high-pressure hydraulic pump (HHHP) that can work under 150°C and 28 MPa to overcome problems of traditional high-temperature plunger pumps. The HHHP is designed with the structure of mechanical division and double cylinder parallel. The control signals of two cylinders are two separate triangle waveforms with 90° phase difference. Because the output waveforms of two cylinders have the same characteristics as the control signals, the HHHP can obtain a stable output after two separate waveforms are superposed. A mononeuron self-adaptive PID control algorithm is also improved by modifying parameters and . Two improved controllers are used to control the two cylinders, respectively, making two displacements of plungers match each other. Therefore, reduced fluctuations and stable pressure output is obtained. Besides simulation, tests on the built prototype test system are carried out to verify the performance of HHHP. Results show that the improved control approach can limit fluctuations to a lower level and the HHHP system attains good outputs under different signal periods and different pressures.

关键词: mononeuron PID control     hydraulic pump     pressure fluctuation    

三峡升船机塔柱混凝土温控防裂技术

杨富瀛,冯晓琳,李晓萍

《中国工程科学》 2013年 第15卷 第9期   页码 55-58

摘要:

三峡升船机塔柱结构复杂,属于高层薄壁结构,混凝土温度受环境温度影响较大,其混凝土温控难度极大。在施工实践中,通过优化混凝土配合比、合理布置混凝土冷却系统、科学调控冷却水温度与通水时间,科学调整外部环境温度、同时引进混凝土养护新材料、新工艺,并且加强对温控的施工管理等措施,保证了塔柱混凝土的施工质量,证明了温控方案的科学合理性。三峡升船机塔柱混凝土温控防裂技术对研究国内外升船机工程温控措施技术水平,提高水电工程混凝土施工质量,节省工程造价等具有重要的参考价值。

关键词: 升船机塔柱     混凝土     温控     防裂     三峡升船机    

闸墩混凝土结构温控防裂措施智能优选研究

黄耀英,丁月梅,吕晓曼,徐佰林

《中国工程科学》 2014年 第16卷 第3期   页码 59-63

摘要:

闸墩混凝土温控防裂是一个与温控措施和材料参数相关的复杂多因素系统优选问题,本文尝试已知混凝土热力学材料参数情况下的温控措施优选,将闸墩混凝土结构内部和表面主拉应力历时曲线和抗拉强度增长曲线关系的最小值作为输入,闸墩表面保温效果、浇筑温度、通水水温、通水时间作为输出,建立了温控措施优选的神经网络模型,采用均匀设计原理进行温控参数组合,并采用水管冷却有限元法仿真分析含冷却水管的闸墩混凝土结构温度场和徐变应力场,获得样本进行学习,以此训练好的网络描述结构主拉应力历时曲线和抗拉强度增长曲线关系的最小值与不同温控措施的非线性关系。将合适的结构主拉应力历时曲线和抗拉强度增长曲线关系的最小值输入训练好的网络,可自动优选出温控防裂措施。算例分析表明,本文建立的温控措施优选神经网络模型是可行的。

关键词: 闸墩     表面保温     通水冷却     浇筑温度     智能优选    

Control of the agglomeration of crystals in the reactive crystallization of 5-(difluoromethoxy)-2-mercapto

Yongli WANG, Shuyuan MA, Xiaodong Lü, Chuang XIE

《化学科学与工程前沿(英文)》 2012年 第6卷 第4期   页码 423-431 doi: 10.1007/s11705-012-1211-7

摘要: 5-(Difluoromethoxy)-2-mercapto-1 -benzimidazole (DMB) was precipitated by adding acetic acid to the DMB sodium salt solution. The spherical agglomeration of DMB during the reactive crystallization in a batch crystallizer was monitored by real-time Particle Video Microscope (PVM). We found that the low feeding rate of acetic acid, high crystallization temperature, low agitation rate or adding seed crystal can facilitate the formation of spherical agglomerates. By using a simple model, the mean crystal agglomerate size of DMB thus predicted is generally in agreement with the experimental data. In addition, the crystallization process of DMB was optimized by a new control strategy of supersaturation to avoid disadvantages brought by agglomeration.

关键词: 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole (DMB)     reactive crystallization     agglomeration     feeding rate     crystallization temperature     agitation rate    

Technology improvements and management innovations in construction of Xiluodu hydropower station on Jinsha River

Qixiang FAN

《工程管理前沿(英文)》 2017年 第4卷 第2期   页码 231-237 doi: 10.15302/J-FEM-2017103

摘要: Hongtao ZHOU, Hongwei WANG, Wei ZENG. [J]. Front. Eng, 2018, 5(1): 78-87.Peter REDFERN, Hua ZHONG. [J]. Front. Eng, 2017, 4(2): 193-200.Ming-zhou Liu,Cong-hu Liu,Mao-gen Ge,Yuan Zhang,Qing-hua Zhu. [J]. Front. Eng, 2016, 3(2): 144-146.Chong-guang Feng,Hao Hu,Feng Xu,Jian Yang. [J]. Front. Eng, 2015, 2(2): 178-181.Yu Zhao,Sheng-quan Wang,Ke-chao Zhu. [J]. Front. Eng, 2015, 2(1): 35-38.Ru-gui Chen,Jia-meng Chen. [J]. Front. Eng, 2014, 1(1): 52-61.An Wang. [J]. Front. Eng, 2014, 1(1): 13-17.

关键词: super-high arch dam     intelligent construction     mass concrete temperature control     structure behavior control     anti-erosion concrete     low-heat portland cement     large-discharge and high-velocity spillway tunnels     large scale underground powerhouse     green hydropower station     sustainable development     Xiluodu hydropower station    

A low power, eco-friendly multipurpose thermoelectric refrigerator

N. Jagan Mohan REDDY

《能源前沿(英文)》 2016年 第10卷 第1期   页码 79-87 doi: 10.1007/s11708-015-0380-8

摘要: There has been an immense endeavor to mitigate global warming in spite of which it has only been worse. This paper presents the design and implementation of a low power and eco-friendly refrigeration system using the thermoelectric effect. The conventional refrigerators make use of complex mechanisms which involves synchronous operation of various units, namely the compressor, condensers, expansion valves, evaporator, refrigerant and so on. But a thermoelectric refrigerator exploits the principle of the Peltier effect, thus avoiding the utilization of these complex components. This even helps curb the release of harmful chlorofluorocarbons (CFCs) into the atmosphere which contributes to the increase in global temperature. Moreover, the temperature can be controlled and set to required values with the help of a microcontroller. Hence, this can be used both for domestic and commercial purposes. The unit does not eject any harmful gases. Therefore, the heat expelled from the unit can be tapped for heating utilities, making the use of this device versatile in its application. Thus this proposal aims not only at reducing the air pollutants by not contributing to it but also at reducing the power consumption.

关键词: low power     eco-friendly     multipurpose     TEC-12706     Peltier effect     microcontroller (P89V51RD2BN)     temperature control    

Assessment of bridge expansion joints using long-term displacement measurement under changing environmental conditions

Youliang DING, Aiqun LI

《结构与土木工程前沿(英文)》 2011年 第5卷 第3期   页码 374-380 doi: 10.1007/s11709-011-0122-x

摘要: This paper addresses the problem of condition assessment of bridge expansion joints using long-term measurement data under changing environmental conditions. The effects of temperature, traffic loading and wind on the expansion joint displacements are analyzed and interpreted, which reveal that measured displacements are observed to increase with an increase in temperature and to decrease with increased traffic loading, while the correlation between displacement and wind speed is very weak. Two regression models are developed to simulate the varying displacements under the changes in temperature and traffic loadings. Based on these models, the effects of the environmental conditions are removed to obtain the normalized displacement. Statistical process control using mean value control charts is further used to detect damage to the bridge expansion joints. The results reveal that the proposed method had a good capability for detecting the damage-induced 1.0% variances of the annual changes in the expansion joint displacements.

关键词: structural health monitoring     displacement     expansion joint     temperature effect     wind effect     traffic loading     statistical process control     suspension bridge    

标题 作者 时间 类型 操作

Development of a dual temperature control system for isoprene biosynthesis in

期刊论文

Constant temperature control of tundish induction heating power supply for metallurgical manufacturing

Yufei YUE, Qianming XU, Peng GUO, An LUO

期刊论文

Temperature effects of shape memory alloys (SMAs) in damage control design of steel portal frames

Xiaoqun LUO, Hanbin GE, Tsutomu USAMI

期刊论文

Temperature control of transfer roller’s bearing based on finite element analysis

Peng ZHANG, Yourong LI, Han XIAO

期刊论文

空调客车内温度控制系统仿真研究

于梅春,张登春

期刊论文

Sliding window games for cooperative building temperature control using a distributed learning method

Zhaohui ZHANG, Ruilong DENG, Tao YUAN, S. Joe QIN

期刊论文

载人航天器微量污染净化装置温度控制研究

庞丽萍,王浚

期刊论文

卫星主动控温回路的设计模型与算法

李运泽,杨娟,宁献文,王晓明,石晓波

期刊论文

A novel high-temperature and high-pressure hydraulic pump based on mononeuron control

Linhui ZHAO, Xin FANG

期刊论文

三峡升船机塔柱混凝土温控防裂技术

杨富瀛,冯晓琳,李晓萍

期刊论文

闸墩混凝土结构温控防裂措施智能优选研究

黄耀英,丁月梅,吕晓曼,徐佰林

期刊论文

Control of the agglomeration of crystals in the reactive crystallization of 5-(difluoromethoxy)-2-mercapto

Yongli WANG, Shuyuan MA, Xiaodong Lü, Chuang XIE

期刊论文

Technology improvements and management innovations in construction of Xiluodu hydropower station on Jinsha River

Qixiang FAN

期刊论文

A low power, eco-friendly multipurpose thermoelectric refrigerator

N. Jagan Mohan REDDY

期刊论文

Assessment of bridge expansion joints using long-term displacement measurement under changing environmental conditions

Youliang DING, Aiqun LI

期刊论文